Skip to main content

National Academies Report Summaried

A subset of the panel that met to synthesize the science on genetic engineering in crops convened at the American Society of Plant Biologists 2016 conference in Austin, TX.  Drs. Robin Buell, Rick Dixon and Neal Stewart discussed the results and process of the panel's conclusions.

There were 20 people on the committee from diverse backgrounds and looked at a wide variety of literature and testimony.  Testimony came from "individuals who have been directly involved in, or who have special knowledge of the question" and they were charged to examine "all credible views".

The committee examined relevant literature, over 1000 publications, saw ~80 personal interviews. Interviews were conducted with many non-scientists with strong anti-GMO views. The entire process was transparent and all information presented was available to the public. Any member of the public could access the information.  All of this was a first for a National Academies Report. 

The central synthesis is that there is no easy differentiation between genetic improvement methods. Any method, including traditional breeding, mutation breeding, transgenics, all have an equal potential to produce deleterious outcomes. 

Environmental, health, social and economic effects were considered in the synthesis of the report. 

Outcomes were from a consensus of 20 diverse individuals with a range of scientific sophistication:


Insect resistance:
  • Reduction in yield losses from insects. 
  • Reduction in the use of synthetic insecticides.
  • Evidence of higher diversity of insects in GE crop areas. This "halo effect" allows farmers that are not growing Bt crops to experience benefits from GE crop production. This was documented in Wan et al, 2012 PLoS One, 7 (7):e42004. 

Herbicide Resistance:
  • Can affect yield positively, but increase flexibility for farmer.
  • Weeds are evolving resistance to glyphosate
  • Integrated weed management approaches were recommended. 
  • Herbicide use in cotton, corn and soybean is generally flat.
  • The rate of resistance to glyphosate is consistent with the trend of weed resistance from any herbicide. 
  • The glyphosate patent expired in 2000 which cut price, and likely contributed to wider use, wider GE crop adoption.
  • Herbicide tolerant crops allow no-till ag and cuts soil loss. 

Yield:

Yield increase rates are not affected on a large scale from biotech plants. However, genes were not added to increase yields, plants were changed so farming can be more predictable and cost less.



The Seralini rats make an appearance in the discussion.


Human Health Effects:
  • The committee went back through negative animal studies and noted how they were not well designed and statistically underpowered.    
  • Feed conversion and other animal metrics did not reflect a problem.
  • Epidemiological data from GE consuming and non-GE consuming countries did not show a difference. 
  • The conclusion was that there was no evidence of adverse health effects. 
  • Seralini was invited to give a presentation, and disappeared from his video screen during the discussion.

Social and economic effects were discussed, and concluded generally favorable economic impacts for farm producers, but there was a lot of heterogeneity in the data.  One issue is that traits are stacked and that not all farmers want stacked traits. There is a difficulty to find some kinds of non-GE seed in certain crops. Future considerations need to be considered with respect to patents, regulation and other product restrictions.

There is concern about how gene editing may be over-regulated.  It is a powerful and successful technology with huge numbers of studies emerging using it.  Cebus has even generated a CRISPR-based herbicide tolerant crop. 

The committee also looked to -omics technologies and how they might work in helping with the safe and effective regulation of genetically engineered crops. Can such technologies be used to really define the composition of plants to ensure more confidence in their safety?  There was a discussion that the public sector could do this job well.  

Predictions suggest that there will be great strides in disease resistance and output traits.  There will be gains in forage crops and crops generated for biofuels.  The long-term reality and environmental impacts are of course not known, but will always be considered.  There also was a recommendation that the pubilc sector play a bigger role in commercialization, and also funds available for examination of potential problems. 

The final synthesis is that it is about the product, not the process, and that the safety focus should be most focused on novel traits. Also that -omics technologies should be used more frequently in safety assessments to have a greater confidence in product equivalence.

The strength of the report comes from its careful language and nuance. There's no evidence that it will solve every problem and no evidence that it is dangerous. The technology has strengths and limitations and when we discuss it we need to consider evidence carefully and look at individual traits. 

This work is a tremendous synthesis from a massive amount of information and a lot of hours from experts in the field. It was a landmark report that will stand as a part of the history of this discussion.

Follow on Twitter at #GEcropstudy








Popular posts from this blog

Scientific American Destroys Public Trust in Science

This is a sad epitaph, parting words to an old friend that is now gone, leaving in a puff of bitter betrayal. 
When I was a kid it was common for my mom to buy me a magazine if I was sick and home from school.  I didn't want MAD Magazine or comic books.  I preferred Scientific American
The once stalwart publication held a unique spot at the science-public interface, bringing us interesting and diverse stories of scientific interest, long before the internet made such content instantly accessible.  It was our trusted pipeline to the new edges of scientific discovery, from the mantle of the earth to the reaches of space, and every critter in between.
But like so much of our trusted traditional science media, Scientific American has traded its credibility for the glitz of post-truth non-scientific beliefs and the profits of clickbait.The problem is that when a trusted source publishes false information (or worse, when it hijacked by activists) it destroys trust in science, trust in s…

Chipotle's Ag-vertising to Fix their Anti-Ag Image

After years of anti-farmer rhetoric, disgusting anti-agriculture videos, and trashing farmer seed choice, Chipotle now seems to have found a love for the American farmer that is as warm and inviting as the gooey core of a steak burrito.  Their new "Cultivate the Future of Farming" campaign raises awareness of the hardship being experienced in agriculture, and then offers their thoughts and some seed grants in order to reverse it. 

But are they solving a problem that they were instrumental in creating? 

The crisis in agriculture is real, with farmers suffering from low prices, astronomical costs, and strangling regulation.  Farmer suicides are a barometer of the crisis.  Farms, from commodity crops to dairies, are going out of business daily. It is good to see a company raising awareness. 


From Chipotle's website- The "challenge is real" and "It's a hard living"-- and companies like Chipotle were central in creating those problems. 

However, Chipotle&#…

Mangling Reality and Targeting Scientists

Welcome to 2019, and one thing that remains constant is that scientists engaging the public will continue to be targeted for harassment and attempted reputation harm.  

The good news is that it is not working as well as it used to.  People are disgusted by their tactics, and only a handful of true-believers acknowledge their sites as credible. 

But for those on the fence I thought it might be nice to post how a website like SourceWatch uses a Wikipedia-mimic interface to spread false and/or misleading information about public scientists. 

Don't get me wrong, this is not crying victim.  I'm actually is screaming empowerment.  I spent the time to correct the record, something anyone can check.  Please look into their allegations and mine, and see who has it right. 

This is published by the Center for Media and Democracy.  Sadly, such pages actually threaten democracy by providing a forum for false information that makes evidence-based decisions in policy issues more challenging.  It…