Tuesday, February 25, 2020

Talking Biotech #227 - Anti CRISPRs


The arms race between bacteria and the viruses that infect them brought the Cas9 and similar editing systems.  These enzymes are essentially a bacterial immune system, and now are being exploited as important tools in genetic engineering.  To counter the bacteria response viruses produce inhibitors of the Cas enzymes. Dr. Joseph Bondy-Denomy is a professor at the University of California San Francisco that studies these inhibitors.  He discusses their discovery and potential applications.