Illumination 2.0

Listen to the podcast here.  Genetically engineered microbes commonly manufacture our vitamins and amino acid supplements, but can they be supplements themselves?  Zbiotics has developed genetically engineered bacteria that may help to metabolize the residues of alcohol consumption, altering the accumulation of the compounds that lead to next-day malaise. These microbes are consumed as a pro-biotic, fortifying the digestive system with a means to break down deleterious metabolites.  Today’s podcast covers the technology with Dr. Zack Abbott from Zbiotics, including a discussion of how a “proudly GMO” product resonates with consumers. Zbiotics LInks: https://www.instagram.com/zbiotics/ https://www.facebook.com/ZBiotics/ https://twitter.com/ZBioticsCompany

Last week I saw an awesome Twitter post.  Dr. Elisabeth Bik posted a figure from a recently published paper in a cancer journal.  The caption simply read, "What's wrong with this image?" I looked at it carefully for two solid minutes.  It was images of baby mice, "pinkies" in the reptile feeding trade, all lined up on their sides with military precision. Some had tumors, some didn't and the figure looked legit.  Until I saw her annotated photo.  She circled examples of how the same little mice babies were cut-n-pasted multiple times, appearing over and over again in different rows.  It was manufactured data. Dr. Bik does a remarkable service to science.  A trained molecular biologist with a substantial CV, she now voluntarily spends her eagle eye scouring the literature for things that don't look quite right.  Like duplicate mice in a manufactured figure.  I had the pleasure of interviewing her for the Talking Biotech Podcast, and she'l...

I discontinued use of Twitter on June 19, 2019.  The account was deactivated, which means I had 30 days to re-activate it before it is permanently deleted.  The clock was winding down, and I had to do a cost/benefit analysis of Twitter.  Certainly p ermanent deletion would mean no more harassment through the medium (that I'd know about). There are about six people and a few 'bots that no longer would harass me.  The problem is that I'd break a connection with 22,000 people that volunteered to receive content.   Today, two days out from permanent deactivation I have a nice article at AgDaily , and a sweet one coming out in The Conversation.  I'd love to share those widely.  The podcast is reaching 1 million downloads with 3,500 per week and almost 200 episodes.  New episodes are not downloaded as much without the Twitter push.  Best of Both Worlds? So it is a necessary evil and I'll have to live with it, but I have to play ...

My entire life I always questioned people that would take their own life or hurt others in rage.  It did not compute for me.  It seems no problem is that big, and there are so many ways to find solutions between the law, social services, and other mechanisms.  But after enduring endless daily harassment from Michael Balter and GM Watch, I deeply empathize with these feelings. It is a dark part of human psychology, and a program in the brain that is triggered from feeling helpless.  It is a reptile brain taking over; backed into a corner with no other choice.  It is the extremes of fight and the extremes of flight, life and death, and I'm feeling that.  I have so much to be grateful for.  I have a wonderful wife, and we hope to have a child on the way soon.  We both were robbed of that opportunity in previous relationships by combinations of tragedies and apathies, and now we are fixing that.  I have a great job, wonderful students, re...

Five years ago today I started the Talking Biotech Podcast.    Everywhere I go I'm amazed to find listeners.  When I don't post an episode exactly at 5AM EST on Saturday morning I get emails complaining. There have been greater than 935,000 downloads.  One guest (who knows me pretty well) learned about the podcast from someone at a wedding, and didn't know that I was the host. Another person stopped me in the airport and asked if I was the host of Talking Biotech-- because he recognized my voice!   Back in 2014 it was a questionable experiment in a new medium.  I didn't want to do it.  But looking back I'm glad I did.  We have created a durable archive that shows where we were, made predictions about where we are going, and then closed the loop with seeing those predictions become realities in many cases.  So thank you to the listeners, the guests, and everyone that shared this experiment with friends.  I appreciate ...

When you teach an inconvenient science there are many that don't want that story heard. Their arguments fall flat, they have no basis for their beliefs- so how does someone derail the freight train of factual information, especially when delivered by a compelling and trusted speaker? It is a special kind of ad hominem -- disqualify the speaker by eroding their earned trust.  And it is easy to do. Trust is an important basis for communication, and it takes a long time to earn.  There are strategies to build trust, and I teach these strategies to fifty audiences a year.  It starts with the Trust Equation.  I didn't make this up, this is well known by psychologists and sociologists.  Trust is a perception an audience feels based on a speaker's competence, reliability, and intimacy-- divided by self-motivation or self-interest.  Different aspects are targeted by those that want to harm a speaker's trust with an audience. How do they do tha...

The internet if filled with unsubstantiated health claims. The bottom line is that in evidence-based medicine we resort to the gold standard of peer-reviewed findings in quality journals, interpreting data derived from double-blind, placebo-controlled trials with significant numbers of participants. The results are reproduced between independent (and frequently competing) research groups, and if they are not, this is reported as well and the original result is held to scrutiny by the field at large. This is the only way to demonstrate efficacy in the absence of human sensory and psychological overlays. Real medicine stands up to this gold standard. Of course, there are those that believe that their homespun remedies and concoctions probably have stronger effects then researched medicines, so those should be offered as alternatives. They tell us that Big Pharma crushes alternatives, just like those scoundrels that accept evidence for the science of evolution conspire to crush Crea...